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Allele Mining: Strategies and ProspectusBY: Dr. Nalin K. Pagi | Category: Biotech-Research | Submitted: 2017-02-21 06:20:42
Article Summary: "Searching for different alleles. Allele - alternative forms of a genetic character found at a given locus on a chromosome. Mining - Searching. It is often referred to as 'dissection of naturally occurring variation at candidate genes/loci' or simply 'allele mining' Allele mining can be visualized as a vital link between effectiv.."
Allele Mining: Strategies and Prospectus
Author: Dr. Nalin K. Pagi
Allele Mining: Searching for different alleles. Allele - alternative forms of a genetic character found at a given locus on a chromosome. Mining - Searching. It is often referred to as ‘dissection of naturally occurring variation at candidate genes/loci’ or simply ‘allele mining’.
Why Allele mining?
(Ashkani et al., 2015)
Sequencing-based allele mining:
Application of allele mining:
Ashkani, S.; Yusop, M. R.; Shabanimofrad, M.; Azadi, A.; Ghasemzadeh, A.; Azizi, P. and Latif, M.A. (2015). Allele Mining Strategies: Principles and Utilisation for Blast Resistance Genes in Rice (Oryza sativa L.). Curr. Issues Mol. Biol., 17: 57-74.
Comai, L., Young, K., Till, B.J., Reynolds, S.H., Greene, E.A., Codomo, C.A., Enns, L.C., Johnson, J.E., Burtner, C. and Odden, A.R., 2004. Efficient discovery of DNA Curr. Issues Mol. Biol. 17:57-74. horizonpress.com/cimb 68 Allele Mining for Blast Resistance in Rice Ashkani et al. polymorphisms in natural populations by Ecotilling. The Plant Journal 37: 778-786.
Ram Kumar, G.; Sakthivel, K.; Sundaram, R.M.; Neeraja, C.N.; Balachandran, S.M.; Shobha Rani, N.; Viraktamath, B.C. and Madhav, M.S. (2010). Allele mining in crops: Prospects and potentials. Biotechnology Advances, 28: 451-461.
Till, B.J., Reynolds, S.H., Greene, E.A., Codomo, C.A., Enns, L.C., Johnson, J.E., Burtner, C., Odden, A.R., Young, K. and Taylor, N.E., 2003. Large-scale discovery of induced point mutations with high-throughput TILLING. Genome Research. 13: 524-530.
About Author / Additional Info:
I am currently working as a Senior Research Fellow at S.D. Agricultural University. I have done Ph.D. in Genetics and Plant Breeding and M.Sc. in Botany. I have also worked with S.D.Agricultural University as a Visiting Lecturer for 2 years.
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