Biotech Articles
Publish Your Research Online
Get Recognition - International Audience

Request for an Author Account   |   Login   |   Submit Article
 
 
HOME FAQ TOP AUTHORS FORUMS PUBLISH ARTICLE
 
 

Nanotechnology and its Application in Medicine - What are Nanoparticles?

BY: Nidhi Uppangala | Category: Healthcare | Submitted: 2010-05-20 22:32:11
       No Photo
Article Summary: "Nanotechnology is usage of nanoparticles artificially prepared by man for medical or industrial applications. Nanoparticles can also be used as semiconductors or imaging agents..."


Share with Facebook Share with Linkedin Share with Twitter Share with Pinterest Email this article
     


INTRODUCTION:

Nanotechnology is usage of nanoparticles artificially prepared by man for medical or industrial applications. In nanosize physical properties such as colloidal properties, solubility, catalytic property of a known element and materials change. These changes in physical properties are used in some of the biotechnology areas like drug delivery and bioremediation. Nanoparticles can also be used as semiconductors or imaging agents.


APPLICATIONS OF NANOPARTICLES:

Nanoparticles made up of inert materials can also be used as catalysts. The nano sized particles have the ability to penetrate into the cell and interact with cellular molecules. Nanoparticles made up of Carbon-based skeletal-type structures like fullerenes or liposome made up of lipid are already used in drug delivery systems and in the cosmetic industry.

Usually lipid based nanoparticles are used in cosmetics, creams, stain-resistant clothing because of their solubility and suspension properties. Carbon based nanoparticles such as chitosan are used as oral protein delivery system, and polymer based nanoparticles are under study for insulin delivery.

Nanoparticles made up of metals or inorganic materials are also used to enhance the MRI and ultrasound results of in vivo imaging. Nanoshells made up of inert materials like gold are used to fight soft tissue tumours because of their ability to absorb radiation at a particular wavelength.
Single stranded DNA can also be detected using positively charged silver nanoparticles.

Nanoparticles loaded with medicine can also be linked with particular antigen so that these nanoparticles are delivered to the particular cell type. This technique is used to treat cancer. Nanoparticles acting as drug delivery system and also imaging agent are used to treat metastatic cancer as this will help doctors in targeting the cancer cell and also they can analyze the effects of the treatment of cancer.

Nanoparticles as drug delivery system along with siRNA treatment were effective in treating cancer. Nanoparticles provide protection to Small interfering RNA until it reaches the target site or tissue. At present this technology is under clinical trial.

Construction of nanoparticles uses the phenomenon known as molecular self-assembly based on hydrogen bonding, van der Waals force and hydrophobic force to construct specific structured nanoparticles. Watson-Crick DNA base pairing is used to construct nucleic acid based nanoparticles.

Another application of molecular self-assembly is used to introduce pore protein into nanoparticles. The opening and closing of these pores allow the release of drug in certain physiological conditions. For example this type of nanoparticles can be used as insulin delivery system. Insulin is delivered when blood sugar level goes down.


ADVANTAGES OF USING NANOPARTICLES:

The advantages of using nanoparticles are the side effects of radiation therapy or chemotherapy are avoided, as nanoparticles are specific to the cancer cell so the neighbouring healthy cells are not being damaged. Nanoparticles reduce the toxic side effect of the treatment. Nanoparticle delivery system improves the bioavailability of the drug by targeting the particular site of action. Also reduce the required quantity of medicine and also the cost of the therapy will be reduced.

The National Cancer Institute funded research is being conducted to use these nanoparticles in the fields like diagnostics, devices, biosensors, microfluidics and therapeutics.

About Author / Additional Info:


Search this site & forums
Share this article with friends:



Share with Facebook Share with Linkedin Share with Twitter Share with Pinterest Email this article

More Social Bookmarks (Digg etc..)


Comments on this article: (0 comments so far)

Comment By Comment

Leave a Comment   |   Article Views: 5553



Additional Articles:

•   Role Of Thyroid Hormones

•   Is Loss of Hairs ... Loss of Life or Health?

•   Compost Input: A Technology For Soil Restoration

•   Environmental Pollution - List of Most Common Pollutants




Latest Articles in "Healthcare" category:
•   Health Care and WHO

•   Current Scenario Of Gene Therapy

•   Targeted Cancer Therapy

•   Custom Made Medicine - Pharmacogenomics

•   Red Biotechnology and Cure of Tuberculosis

•   Patho-Biotechnology: Solution to Fight Antibiotic Resistance Bacteria?

•   A Baby Please With a Cheek Dimple...

•   Ribonucleic Acid Interference

•   Biomarker in Cancer Prognosis, Detection and Treatment

•   Adjuvant Therapy For Treating Cancer

•   DNA Microarray and Protein Microarray

•   DNA Vaccine: Vaccine of Next Generation

•   Cancer Immunotherapy Using Monoclonal Antibodies

•   Vaccines to Treat Cancer!

•   Tumor Marker and Cancer Detection

•   Targeted Therapy and Cancer Treatment

•   Enzyme Linked Immunosorbent Assay : A Biotechnology Technique

•   Lycopene as Anti-cancer Agent

•   Seaweed Shows Anti-cancer Activity: Alternative Cancer Therapy



Important Disclaimer: All articles on this website are for general information only and is not a professional or experts advice. We do not own any responsibility for correctness or authenticity of the information presented in this article, or any loss or injury resulting from it. We do not endorse these articles, we are neither affiliated with the authors of these articles nor responsible for their content. Please see our disclaimer section for complete terms.
Page copy protected against web site content infringement by Copyscape
Copyright © 2010 biotecharticles.com - Do not copy articles from this website.

ARTICLE CATEGORIES :
Agriculture Bioinformatics Applications Biotech Products Biotech Research
Biology Careers College/Edu DNA Environmental Biotech
Genetics Healthcare Industry News Issues Nanotechnology
Others Stem Cells Press Release Toxicology  


  |   Disclaimer/Privacy/TOS   |   Submission Guidelines   |   Contact Us