Biotechnology Articles Publish Your Biotechnology Research/Articles Online

Share your knowledge - Get Recognition | International Audience - Great Readership
  

Home | Submit Articles | Login   
 
ALL Categories AGRICULTURE CAREERS GENETICS HEALTHCARE ISSUES NEWS STEM CELLS
 
 

Pinworms: The Worm That Causes Nocturnal Anal Itching in Children

BY: Zandro Cabaral | Category: Healthcare | Submitted: 2011-01-12 20:21:47
 

   Author Photo
•    Post a Comment

Share this article with friends:



Share with Facebook Share with Linkedin Share with Twitter Share with Pinterest Email this article

More Social Bookmarks (Digg etc..)


Parasites are organisms which depend on other organisms for nutrition to live. Most parasites are in the form of worms and flukes known as Helminths. These organisms are acquired by the hosts from the food that they eat, water and soil. Parasitism is most common in children but can also happen in adults. Some parasites derive benefit without causing injury to the host. This is called Commensalism type of parasitism. There is also a type of parasitism wherein the two organisms cannot exist independently. This is called Symbiosis. The Mutualism type is wherein the two organisms are both beneficial to each other.

Enterobius vermicularis, commonly known as the pinworm or the seatworm, is the most common cause of parasitism in children in the United States. Pinworms have the broadest geographic range of any helminth, and are the most prevalent helminth infection in the USA and Western Europe. It is commonly found in school-aged children, though it is seen in adults as well. The worms are small, white, and threadlike, with the larger females ranging between 8-13 mm x 0.3-0.5 mm and the smaller males ranging between 2-5 mm x 0.1-0.2 mm. Females also possess a long, pin-shaped posterior end from which the parasite's name is derived. They dwell primarily in the cecum of the large intestine, from where the gravid females migrate at night to lay up to 15,000 eggs on the perineum. Pinworm eggs are flattened asymmetrically on one side, ovoid, approximately 55 mm x 25 mm in size and embryonate in six hours. It has been speculated recently that Enterobius vermicularis also plays as an intermediate host for another helminth which is Diantamoeba fragilis. Parasitism of this organism is manifested by nocturnal anal pruritus or itchiness. Skin abscess can result due to excessive scratching of the perianal skin. Adult pinworms dwell in the cecum and appendix disrupting proper absorption which is manifested by malnutrition.

Humans acquire infection through the ingestion of eggs which hatch in the small intestine and become larvae. The larvae develop to adults separately as males and females in the colon and mate. Fertilized females migrate to the anus at night to release eggs at the perianal skin. These eggs hatch into infective larvae 6 hours after.

The most common manifestation of pinworm parasitism is the nocturnal anal pruritus or night time anal itching. This is caused by the migration of female pinworms to the anus to lay eggs, specifically, insertion of the tail pin into the mucosa for ovideposition, and scratching leads to finger contamination and subsequently the spread of ovum to others. The scratching may also excoriate the skin and lead to secondary bacterial infections. Secondary symptoms, which are due to disturbed sleep caused by pruritis, include anorexia and irritability. However, pinworm infection is not always harmless, as it has been implicated in causing appendicitis, as high as 2.39% of cases in developing countries, intestinal obstruction, intestinal perforation, enterocolitis mimicking Crohn's disease, and eosinophilic ileocolitis.

The most commonly used technique of collecting eggs of pinworms for sample and diagnostics is the Cellophane technique. This must be done early morning. A Scotch tape is mounted to the perianal skin; the tape will then be examined by microscopy for the presence of D-shaped ova that stick in the tape. These eggs may also be stained blue with lactophenol cotton blue, which aids in detection and identification. The sensitivity of this test when performed for three consecutive mornings is 90%. Anal swabs or 'Swube tubes" may also be used. Extra-intestinal infections may require more invasive diagnostic tests. One case diagnosed via colonscopy followed by confirmation via microscopy and infections of the female genital tract usually require laparotomy and excision of granulomas for a conclusive diagnosis. Pre-operative diagnosis of finding the parasite via cervical smears, vaginal wet mounts, and vaginal pooled specimen is possible but difficult. Alternatively, the adults may be seen in stool or toilet paper, though the ova and larvae are rarely present in either the stool or urine.

The drugs recommended in eliminating Enterobius vermicularis are the Antihelminthics such as Mebendazole and Pyrantel pamoate. Antihelminthics are usually taken orally, in a quantity appropriate to the child's weight, given once a day at bedtime as a single dose.

About Author / Additional Info:



Comments on this article: (0 comments so far)

Comment Comment By Comment Date

Leave a Comment   |   Article Views: 5624



Additional Articles:
•   Development and Applications of Nanobubbles
•   Research and Development of Bacterial Genomic Size
•   Laboratory Data For Blood Test
•   Fungi as Builders For Nanomaterials

Latest Articles in "Healthcare" category:
•   Health Care and WHO
•   Current Scenario Of Gene Therapy
•   Targeted Cancer Therapy
•   Custom Made Medicine - Pharmacogenomics
•   Nanotechnology and its Application in Medicine - What are Nanoparticles?
•   Red Biotechnology and Cure of Tuberculosis
•   Patho-Biotechnology: Solution to Fight Antibiotic Resistance Bacteria?
•   A Baby Please With a Cheek Dimple...
•   Ribonucleic Acid Interference
•   Biomarker in Cancer Prognosis, Detection and Treatment
•   Adjuvant Therapy For Treating Cancer
•   DNA Microarray and Protein Microarray
•   DNA Vaccine: Vaccine of Next Generation
•   Cancer Immunotherapy Using Monoclonal Antibodies
•   Vaccines to Treat Cancer!
•   Tumor Marker and Cancer Detection
•   Targeted Therapy and Cancer Treatment
•   Enzyme Linked Immunosorbent Assay : A Biotechnology Technique
•   Lycopene as Anti-cancer Agent


Important Disclaimer: All articles on this website are for general information only and is not a professional or experts advice. We do not own any responsibility for correctness or authenticity of the information presented in this article, or any loss or injury resulting from it. We do not endorse these articles, we are neither affiliated with the authors of these articles nor responsible for their content. Please see our disclaimer section for complete terms.
Page copy protected against web site content infringement by Copyscape
Copyright © 2010 biotecharticles.com - Do not copy articles from this website.
| Home | Disclaimer | Xhtml |