Publish Your Research Online
Get Recognition - International Audience
Request for an Author Account | Login | Submit Article
|HOME||FAQ||TOP AUTHORS||FORUMS||PUBLISH ARTICLE|
Human Sperm Created Using Embryonic Stem CellBY: Nidhi Uppangala | Category: Industry-News | Submitted: 2010-05-28 20:31:52
Article Summary: "First time human sperms are created in the laboratory using embryonic stem cells. Researchers at the Newcastle University and the NorthEast England Stem Cell Institute (NESCI) created human sperms using a new technique. Research was led by Professor Karim Nayeria..."
First time human sperms are created in the laboratory using embryonic stem cells. Researchers at the Newcastle University and the NorthEast England Stem Cell Institute (NESCI) created human sperms using a new technique. Research was led by Professor Karim Nayeria.
Technique used to produce In vitro Derived Sperm:
1. Embryonic stem cells are cultured in a new medium containing the vitamin A derivative known as retinoic acid. In this new culture media embryonic stem cell differentiated into the germline stem cells.
2. Differentiated germline stem cells produced a protein. These proteins were stained with green fluorescent marker and were extracted from the media using laser by FACSTM (fluorescence-activated cell sorting) method.
3. Further differentiation of these germline stem cells expressed marker proteins which are specific to primordial germ cell, spermatogonial stem cells, spermatocytes, spermatids and then finally the sperm.
4. These marker proteins indicate that the germline stem cells are differentiated into male gametes or human sperms with haploid number of chromosomes. These human sperms are known as In vitro derived sperm.
5. Embryonic stem cells with XY chromosomes but not with XX chromosomes are differentiated into early stage sperms known as spermatagonia, indicating that the genes which are present in the Y-chromosome (male chromosome) play a very important role in the production of the sperms.
This Research will lead to better understanding of developmental biology of human sperms. This new invention will help researchers to better understand the infertility in men. Like what are the causes for male infertility and also why these changes happens in some men. These understanding will help in developing new methods or techniques, to help infertile couples to have a child, of their own.
This will also allow researchers to study the effect of toxins on cells that are involved in reproduction. For example young boys with cancer like leukaemia treated with chemotherapy will suffer from infertility throughout their life. These studied may help in developing new solution for this problem.
This will also help scientists to better understand the process of sex linked inheritance of genetic diseases.
The in vitro derived sperms will not and cannot be used for fertility treatments. Law of the developed country also prohibits the usage of in vitro derived sperms for fertility treatment. Researchers of this technique say that they are only interested in understanding the causes for infertility in some men and they are hoping to develop new techniques as a answer to this infertility problem.
About Author / Additional Info:
Comments on this article: (1 comments so far)
• Journey to Bacillus Thuringiensis (BT) Crops
• Breakthrough Cures: Basics of Biotechnology in Medicine and Treatment
• Plant Based Edible Vaccine
• Industrial Biotechnology Evolution and Recent Developments
Latest Articles in "Industry-News" category:
• The New and Easy Way to Obtain P450-metabolites and N-glucuronides For Metabolit
• Use of Jelly Fish in Preventing Bioterrorism
• Latest Biotechnology Industry News and Pharmacy News
• Personalised Cancer Vaccine in a Week
• First Synthetic Organism
• Gut Microbiota May Play a Role in Host Adiposity
• Latest in Pharmaceuticals : Sleep Drug: MK-4305 and Plastic Antibodies
• Biotech News From the World of Medicine
• Contribution of Biotechnology to the Latest Trends in Cardiac Care
• Biotechnology in the Manufacture of Textiles
• Biotechnology Companies in South Africa: Human Health
• Joule Unlimited - Pioneering Alternate Fuel and its Advantages
• Starch as Vitamin Carrier - A New Technology
• Phase IV Studies - A Market With a Proactive Approach for Growth of a Pharmaceutical Firm
• ISO-9000 Requirments, Effectiveness and Advantages
• Inoculum Preparation in Seed Lab of Fermentation Industries
• Enjoy the Benefits of Drinking a Cup of Coffee
• Understanding the Team Insurance Policy (Group Insurance)
• R&D: The Poignant Loneliness--Brief Case Studies of 8 New Listed Drugs
Important Disclaimer: All articles on this website are for general information only and is not a professional or experts advice. We do not own any responsibility for correctness or authenticity of the information presented in this article, or any loss or injury resulting from it. We do not endorse these articles, we are neither affiliated with the authors of these articles nor responsible for their content. Please see our disclaimer section for complete terms.
Copyright © 2010 biotecharticles.com - Do not copy articles from this website.
ARTICLE CATEGORIES :
| Disclaimer/Privacy/TOS | Submission Guidelines | Contact Us