CAN WE BE YOUNG FOREVER?
Right now a newborn can expect to live an average of 76 years. With recent discoveries in biology, many scientists predict that life expectancy will continue to triple-digits. In fact, if they are correct, humans shouldn't have to die at all in the future.
"Over half the baby boomers here in America are going to see their hundredth birthday and beyond in excellent health. We're looking at life spans for the baby boomers and the generation after the baby boomers of 120 to 150 years of age." - Says, Dr. Ronald Klatz of the American Academy of Anti-Aging.
"Anti-aging medicine is not about stretching out the last years of life. It's about stretching out the middle years of life... and actually compressing those last year's few years of life so that diseases of aging happen very, very late in the life cycle, just before death, or don't happen at all." -- says Dr. Klatz.
WHY DO WE AGE AND DIE ?
All cells whether found in unicellular or muticellur individuals have their individual period of existence, which is described as cell cycle. They begin in the division of the parent cells, grow in size and cease at the end of the period of maturation and undergo specialization for specific functioning. The cells maintain themselves for a short period at this stage and then deteriorate or else enter division losing their individuality into a pair of daughter cells. This a complex process that involves every cell and organ in the body and that leads to the deterioration of many body functions over the lifespan of an individual.
As the body ages our cells lose some of their ability to regenerate and to perform the functions they were designed to perform. Our hair turns gray, eyesight and hearing fade and even our organs begin to deteriorate. With age, for example, the skin loses its elasticity and injuries heal more slowly than in childhood. The same holds true for bones, which turn brittle with age and take much longer to heal when fractured. Lung tissue also loses its elasticity and the muscles of the rib cage shrink. Blood vessels accumulate fatty deposits and become less flexible, which results in arteriosclerosis. The reduced capacity to regenerate injured tissues or organs and an increased tendency to infections and cancers are probably the most prominent characteristic of senescence. Senescence occurs when the catabolic activity taking place in the body slowly dominates the anabolic process. They are called the final stage of cellular aging.
Most scientists will tell you that the aging process is brought about by changes in the proteins, lipids and nucleic acids such as DNA and RNA that make up our cellular structure.
Experiments have shown that this aging process can be slowed down by introducing certain changes to aging cells, and when those changes are introduced, the cells revitalize to the point that they function as if they were much younger.
As scientists continue searching for the equivalent of the 'fountain of youth' by taking closer looks at cellular structures and the impacts of stress and diet on aging , following was researched to know about aging and how to reverse it.
"Telomerase is a new theory of aging that holds many promising possibilities for the field of anti-aging medicine."
Telomerase is an enzyme that is responsible in maintaining the telomeres as a whole. Telomeres are known to be the structures found at the chromosomes end which are characterized by thousands of repetition of the sequence of nucleotide TTAGG. If this telomere is shortened rather than lengthened, it can cause subsequent damage in the cells of the body because of its inability to efficiently duplicate. Scientists observe that the length of telomere chains becomes shorter as we grow older. Eventually the telomeres become so short that cell replication produces lethal errors or missing pieces in the DNA sequence, ending the cell's ability to replace itself. This point, when the cell has lost vital DNA code and cannot reproduce, is called the Hay flick limit. It's the measure of how many times a cell can copy itself before it dies.
Some cancer researchers believe that the creation of a targeted telomerase inhibitor may actually be able to stop a cancer cell's ability to divide--thus stopping the spread of cancer. It is even widely believed that specialized telomerase enzymes might actually be able to convert cancer cells back into normal cells!
Once of the most confounding issues faced by researchers is the fact that the aging process is not predictable or uniform across all of humanity. Each of us age differently based upon our genetic makeup, degree of stress, dietary habits, environment, etc. As a matter of fact the only thing all of us share in common is the fact that we are all aging and all our cells will eventually give out.
ERASING SIGNS OF AGING IN HUMAN CELLS NOW A REALITY
Insert's AVENIR "Genomic plasticity and aging" team, directed by Jean-Marc Lemaitre, Insert researcher at the Functional Genomics Institute have recently succeeded in rejuvenating cells from elderly donors (aged over 100) BY using a strategy that consisted of reprogramming cells using a specific "cocktail" of six genetic factors, while erasing signs of aging. Cocktail of genetic factors included OCT4, SOX2, C MYC, KLF4, NANOG and LIN28.
Firstly they multiplied skin cells (fibroblasts) from a 74 year-old donor to obtain the senescence characterized by the end of cellular proliferation. They then completed the in vitro reprogramming of the cells. Using this new "cocktail" of six factors, the senescent cells, programmed into functional is cells, re-acquired the characteristics of embryonic pluripotent stem cells. Hence, they recovered their capacity for self-renewal and their former differentiation potential, and do not show any traces of previous aging
DRUG THAT REVERSES 'ACCELERATED AGING' IN HUMAN CELLS
The drug Rapamycin has been found to reverse the effects of Hutchinson-Gilford progeria syndrome, a fatal genetic disease that resembles rapid aging, in cells taken from patients with the disease. No treatments currently exist for the disease, which is typically fatal by age 12. Children with progeria have health issues typically associated with old age, including balding, hardened skin, pain in joints, hip dislocations, and heart disease.
Rapamycin, an immunosuppressant drug used to prevent rejection of transplanted organs, has already been shown to extend life span in healthy mice. Researchers hope the findings will provide new insight into treating progeria as well as other age-related diseases.
Secondly a supplement called RENEUVEâ„¢ is found that re-introduces critical Anti-Aging and Immune System-Strengthening Telomerase Enzymes and Peptides into your body and then distributes these enzymes to all cells within your body.
RENEUVEâ„¢ is taken orally every 6 months. It is sold as a dietary supplement only, and is not sold to treat, prevent, diagnose, or cure any diseases or illnesses.
RENEUVEâ„¢ resets your "body time clock" enabling cellular rejuvenation and well being .it renews" your DNA and enables your body to produce more life-supporting stem cells and also has the ability to support a physical "age reversal" from the inside out--without any side effects!
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