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Most Recent Biotech Research Articles.
  • Marker-Free Transgenic Plants    By: Dr. Suresh Kaushik

    Public concerns about the issue of the environmental safety of genetically modified plants have led to a demand for technologies allowing the production of transgenic plants without selectable (antibiotic resistance) markers. >> Category: Biotech Research
  • Random and Insertional Mutagenesis for Functional Genomics in Plants    By: Dr. S. V. Amitha Mithra

    The turn around time of structural genomics in plants and animals has been coming down in exponential manner since the advent of New Generation Sequencing technology. However, the functional genomics is not keeping pace with the advancement of structural genomics. Mutagenesis, both random and insertional, is one of the important means for functional genomics of all organisms. >> Category: Biotech Research
  • Efficient Purification of Alpha Amylase by Affinity Precipitation    By: Hareepriyaw M

    Alpha-amylase is one of the many industrial enzymes that is utilized in several industrial applications like high-fructose corn syrup, desizing of textiles, ethanol production, detergents, hydrolysis of oil field drilling fluids, recycling of paper and modified starches. >> Category: Biotech Research
  • Growth of E.coli in the medium with Tender coconut water    By: Hareepriyaw M

    Tender coconut water (TCW) with Nitrogen source an economical growth medium for the production of recombinant proteins in Escherichia coli. >> Category: Biotech Research
  • Genome Sequence of Cucumber Reveals Mechanism of Monoecy    By: Dr. Prasanta K. Dash

    Cucumber Genome has been decoded by a hybrid approach of genome sequencing. Subsequently, resequencing of 115 cultivars across the globe revealed the mechanism of evolution, absence of whole genome duplication, formation of special organs and mechanism of sexual dimorphism in this important crop of cucurbitaceae family. >> Category: Biotech Research
  • Impact of Phaseolus Vulgaris Extract on Cyanobacterial Growth    By: Hareepriyaw M

    Phaseolus vulgaris consists of phytohaemagglutinin or PHA. PHA is a lectin that has its role in cell proliferation and defence mechanisms. The present study concentrates on protein synthesis and growth of Nostoc ellipsosporum NCIM 2786 on the Fog’s medium which is supplemented with the extract of Phaseolus vulgaris rich in phytohaemagglutinin and glucose. Statistical analysis of medium components was performed by Plackett-Burman method. >> Category: Biotech Research
  • Engineering Bt Toxins for Effective Insect Control    By: Rhitu Rai

    This article focuses on biology and genetic engineering of the most successful biopesticide Bacillus thuringiensis and how biotechnological tools have helped in improving upon the Bt toxin's efficiency as well as widening the host spectrum. Few strategies to cope with resistance development in insects are also dealt with. >> Category: Biotech Research
  • Method of Effective DNA Isolation from Terminalia arjuna    By: Hareepriyaw M

    Terminalia arjuna is commonly called as Roxburgh and grows to a height of 20 to 30 meters. It belongs to the plant family of Combretaceae. The bark of Terminalia arjuna is useful in treating heart failure, coronary artery diseases, hypercholesterolemia and more >> Category: Biotech Research
  • Antimicrobial and Antioxidant Features of Nutmeg    By: Hareepriyaw M

    Nutmeg is the dried seed of the Myristica fragrans Houtt. It has anti-cancer, anti-inflammatory and anti-diarrheal properties. Nutmeg also acts as a memory enhancer and aphrodisiac. This study concentrates on investigating the antioxidant and antimicrobial properties of nutmeg with the help of extracts of methanol, ethanol, acetone, butanol and nutmeg aqueous extracts. >> Category: Biotech Research
  • Protein Bodies in Transgenic Plants | Case Study-Tobacco Plant    By: Hareepriyaw M

    Elastin like polypeptide and hydrophobin fusion proteins expressing transgenic tobacco plants consisted of intracellular protein bodies. >> Category: Biotech Research
  • Zinc Finger Nuclease (ZFN) - Modify human genome precisely and efficiently    By: Priyanka Chaudhary

    It is possible to target the DNA sequences probing gene function. Designer zinc finger proteins (ZFPs) are the sequence specific tools which are used to manipulate a gene of interest at genomic level. Several methods are being used to modify the human genome precisely and efficiently. These methods hold great promise to revolutionize the gene therapy arena. One of these promising technologies ZFN. >> Category: Biotech Research
  • Sponge Associated Microbes and its Biotechnological Potential    By: Balaram Mohapatra

    This article focuses on microbes those are symbiotically associated with marine sponges in deep oceans and their novel as well as biotechnological potential. As marine environment is most diverse and well maintained in terms of energy, productivity, homeostasis and eco sustainability, it is important to study the microbial diversity, their beneficial biotechnological potential for sustainability >> Category: Biotech Research
  • Epilepsy Gene LGI2    By: Shivani Sharma

    After the discovery of LGI2 (the gene linked to epilepsy), major principles can be postulated in the field of therapeutics. Not only can a better understanding can be ensured to be gained of epilepsy disorder and mechanisms but also improved medications and treatments can be developed in order to reach the target of curing the vast majority of people suffering from this very disease >> Category: Biotech Research
  • Common Feed Additives in Animal Nutrition    By: Bimrew Asmare

    A range of feed additives, many of biotechnological origin, are known to modify rumen fermentation. These biotechnological products can help in improving animal feed its nutrients e.g. silage, biological treatment with microorganisms or through modifying the digestive and metabolic systems of the animals, i.e. modifying rumen ecosystem, to enable them to make better use of the available feeds. Therefore, supplementation of the diet as a means of improving nutritive value is becoming commonplace. The use of feed additives to improve post ingestion quality of feeds is on the verge of delivering practical benefits to animal production systems. >> Category: Biotech Research
  • DNAzymes: Introduction and DNAzymes in Cancer Treatment    By: Priyanka Chaudhary

    DNAzymes are the highly useful tools in molecular biology and now-a-days they are being used in clinical research. DNAzymes are the potent analytic tool available to molecular biologists. There are several techniques which are used for gene silencing which include DNAzymes, short interfering RNAs (siRNAs), antisense oligonucleotides and the ribozymes mainly. >> Category: Biotech Research
  • Transfer of Male Sterility to Cauliflower Varieties Through Inter-Generic Crosses    By: Dr. Swati Saha

    Male sterility described as inability of the plant to produce fertile pollen is widespread in angiosperms and provides one of the most efficient means of directed pollination for the large-scale production of hybrid seeds in crops. Male sterility manifests itself usually in floral development as an incompatibility of nuclear-mitochondrial interaction in alloplasmic lines derived from wide hybridization, which carry nuclear and mitochondrial genomes from different species. >> Category: Biotech Research
  • Tomato Genome For Comparative Genomics    By: Dr. Amolkumar U. Solanke

    The tomato genome sequenced by International Tomato genome Sequencing Consortium presently serves as a powerful resource to identify gene functions and clone agronomically important genes and alleles not only from tomato but also from less studied crop species through comparative analysis across the Solanaceae species. >> Category: Biotech Research
  • SNPs in Complex Plant Genomes - Discovery and Genotyping    By: Dr. S. V. Amitha Mithra

    Next Generation Sequencing (NGS) technologies have made whole genome sequencing and SNP discovery in many crop species possible. Still there are a lot of issues to be resolved in complex genomes, which is more prevalent in angiosperms, regarding sequencing and SNP discovery . These issues and the way forward are discussed in this article. >> Category: Biotech Research
  • Omics Approaches for Identification of Stress Responsive Genes    By: Dr. Amolkumar U. Solanke

    Comparative study of transcripts, proteins and metabolites in stressed and un-stressed crop plants help to pick important stress associated genes, products which can be useful in providing various levels of tolerance. These three omics approaches have a fundamental difference from genomics in that these are dynamic in nature where as genome is static across the tissues and lifetime of an individual.. >> Category: Biotech Research
  • Green Fluorescent Protein (GFP) - The Protein That Revolutionized Science    By: Shivani Sharma

    Ever since the study of biochemical and molecular mechanisms inside living beings started, a need was felt to examine these processes more closely so as to understand the life better. From the propagation of a disease-causing pathogen/molecule inside the body to development of a particular type of cell. How a cell initiates its functions inside body, how the developmental stages occur in a cell, h >> Category: Biotech Research
  • Genetic Transformation Using Microinjection    By: Shivani Sharma

    Genetic transformation of animals is the introduction/removal of new genes into the genome of an organism. This is also widely referred to as genetic engineering. This genetic manipulation doesn't have any effects on the other genes' working and the rest of the genome functions in a usual manner. >> Category: Biotech Research
  • Biotechnological Approaches for Isolating the Genes of Agronomic Significance    By: Dr. N. C. Gupta

    Identification and isolation of the novel genes from different plant species is an important aspects of the molecular biology research. This article mainly emphasize the various biotechnological approaches those has been been routinely utilized for cloning the genes of agricultural importance. >> Category: Biotech Research
  • Characterization of a Plant RNA Pol-II Promoter Sequence    By: Dr. N. C. Gupta

    Detailed analysis of a promoter sequence is usually required to firmly validate their function as well as decipher the way for their possible implication in crop improvement program. >> Category: Biotech Research
  • Isolation of a Plant Promoter by T-DNA Insertional Mutagenesis    By: Dr. N. C. Gupta

    Promoter of a gene plays an important role in regulating the expression behavior of a gene and determines when, where and to what extent that gene will be expressed. There are several strategies known to identify a plant promoter in which insertional mutagenesis approach is comparatively technically less demanding and more expedient. Once the promoter trapped line becomes available one of the appr >> Category: Biotech Research
  • Epigenetics: Applications in Crop Improvement    By: Dr.Sunil S Gomashe

    The article deals with role of epigenetics in crop imrovement and its wide applications >> Category: Biotech Research
  • Agricultural Biotechnology: From Green Revolution to Gene Revolution    By: Dr. Suresh Kaushik

    The gains in food production provided by the Green Revolution have reached their ceiling while world population continuous to rise. Agricultural biotechnology is that area of biotechnology involving application to agriculture. New developments in agricultural biotechnology are being used to increase the productivity of crops .. >> Category: Biotech Research
  • Successful Single Cell Protein Production From Pineapple Waste    By: Shivani Sharma

    Single cell protein production is at the peak of infancy today. The production of single cell proteins can be accelerated by genetically modifying the micro-organisms employed for the purpose according to the need. >> Category: Biotech Research
  • Blue Eye Mutation: Inheritance From a Single Ancestor    By: Shivani Sharma

    The blue eye mutation dates back to 6-10 thousand years ago when the main gene associated with the eye color, OCA2, underwent a mutation in a single human. Ever since that single event, no mutations have arisen in this gene and thus is considered most likely to be the cause of all the blue-eyed humans alive presently. >> Category: Biotech Research
  • Salmonella - From a Disease to a Cure    By: Maitree Baral

    Salmonella has set milestone in the biotech research; starting from a disease causing agent to an anti cancer agent. >> Category: Biotech Research
  • Bioreactor Operations- Vortex Flow Separation For Separating Cells    By: Meenu Kumar

    The technique of culturing mammalian cells on a large-scale is frequently performed in airlift reactors or stirred tank in batches. In order to achieve product concentrations and high cell densities fed-batch processes were introduced. >> Category: Biotech Research
  • Drug-Eluting Stents and Coronary Angioplasty    By: Meenu Kumar

    Percutaneous Transluminal Coronary Angioplasty (PTCA) is the procedure used to widen the coronary stenosis without the need for an open-surgical procedure. PTCA is also applied for treating stenosis of carotid arteries, which supply blood to the brain. >> Category: Biotech Research
  • The Role of Lactic Acid Bacteria in Preventing Respiratory Infections    By: Meenu Kumar

    The respiratory tract serves as the main pathway for pathogenic microorganisms to enter. Microorganisms replicate in the respiratory tract before spreading throughout the body. Acute lower respiratory tract infection (RTI) constitutes a pervasive and persistent health problem. >> Category: Biotech Research
  • Nanobiotechnology in Cardiovascular Disorders    By: Meenu Kumar

    Several nanosystems and nanodevices are available today for the sequencing of single DNA molecules. In the future, it is quite likely that numerous applications based on inorganic nanostructures will become available in medicine and biology as markers. >> Category: Biotech Research
  • Ethanologenic Bacteria and its Development    By: Meenu Kumar

    The rising cost of petroleum along with human dependency on crude-oil imports has opened up an opportunity for chemicals and bio-based fuels to become economically competitive. With new technologies developing on one side, petrochemicals and petroleum-based automotive fuels are effectively replaced with plant and plant-derived materials. >> Category: Biotech Research
  • Therapeutic Proteins and their Immunogenecity    By: Meenu Kumar

    In 1982, the first recombinant protein derived from DNA, for human use, was marketed as the human insulin. Since then, many recombinant proteins were introduced among which epoetins and interferons are some of the widely used drug products in the world today. >> Category: Biotech Research
  • DNA Microarrays and Design Formats    By: Meenu Kumar

    When physiological changes occur, some genes tend to become more active while other genes become inactive. In most biological processes, more than one gene is involved. In order to understand the functioning of an organism, scientists have examined many of an organism's life process simultaneously to understand how they respond to various changes over time. >> Category: Biotech Research
  • The Role of Monoclonal Antibody in Organ Transplant    By: Meenu Kumar

    Monoclonal antibodies are used in transplantation in order to prevent the host immune recognition of the donor tissue. Allograft tissue is impaired to the host immune response by two ways namely: antibody-mediated rejection and cellular-mediated rejection >> Category: Biotech Research
  • PET Scan in Stem Cell Therapy    By: Meenu Kumar

    Chronic heart failure is the major contributor to today's mortality and morbidity. It forms the final pathway for most heart disease forms among which coronary heart disease is the common contributor. >> Category: Biotech Research
  • The Role of Endometrial Cells in Treating Cardiac Failure    By: Meenu Kumar

    Heart failure, as we all know, is one of the major reasons of mortality and morbidity world-wide. Recent findings have stated that heart valve can undergo regeneration, which ideally can eliminate the usage of bovine and porcine valve replacements. This involves the usage of an effective allogeneic product, in conjunction with an effective delivery system. >> Category: Biotech Research
  • Industrial Biotechnology Evolution and Recent Developments    By: Gayathri Raghavan

    An Introduction to Industrial Biotechnology and its history. Industrial Biotechnology provides a wide range of new approaches to resource management, cost reduction in production, and tends to cater the higher requirements in Biotechnology, by targeting off-shoots at grass root level. Examples describing this third-wave biotechnology are the laboratory synthesis of Interleukins, monoclonal antibodies, Insulin. >> Category: Biotech Research
  • Biomarkers For Alzheimer's Disease    By: Geetanjali Murari

    This article deals with the treatment and diagnosis of the most common neurodegenerative disorder affecting many people worldwide. The early diagnosis of Alzheimer's would help the patients to cope up with the disease. >> Category: Biotech Research
  • Genomics Tools For Microbial Ecology: New Directions    By: Dr. Suresh Kaushik

    Microorganisms have been integral to the history and function of life on Earth. They have played important roles in Earth's climate, geological, geochemical and biological evolution. Microbial ecology examines the diversity and activity of microorganism in Earth's biosphere. The applications of genomics tools such as DNA cloning, DNA sequencing, polymerase chain reaction, DNA re-association kinetics analysis, fluorescent in situ hybridization (FISH), microarray technology, representational difference analysis, 2-D gel electrophoresis, mass spectrometry and gas chromatography have revolutionized microbial ecological studies. >> Category: Biotech Research
  • VRC01- New Vaccine to Target HIV    By: Geetanjali Murari

    Finding a cure for HIV/AIDS has always been a hot topic of research among the researchers and scientists. This article deals with the new vaccine designed to target the epidemic causing virus. >> Category: Biotech Research
  • Superhumans- Genetically Modified Humans    By: Geetanjali Murari

    We have seen many supernatural movies and read numerous novels related to superman. This fictitious character can do anything, make any impossible thing possible. But now this concept is no more imaginary. After producing genetically modified crops, vegetables, fruits, animals, now scientists are researching on genetically modified humans. Lets have a look at its consequences... >> Category: Biotech Research
  • ELQ-300 : The Invention of a New Anti-malarial Drug    By: Geetanjali Murari

    This article depicts the discovery of new drug which can combat the malarial parasite. The recent discovery was done under the Medicines for Malaria Venture (MMV) project which include Oregon Health & Science University in Portland, Drexel University in Philadelphia, and Monash University in Australia and University of South Florida. >> Category: Biotech Research
  • Assisted Reproduction- ICSI (Intra Cytoplasmic Sperm Injection)    By: Geetanjali Murari

    The innovative research in biotechnology has made every impossible work possible. The discovery of ICSI, an assisted reproduction can aid in the male infertility. Now, even the infertile men can have their own children. This article depicts the method, merits and risks associated with this technology. >> Category: Biotech Research
  • Genetic Information- Storage and Retrieval    By: Gayathri Raghavan

    In conventional sense, a library is an information repository that is catalogued for easy information retrieval and use. Biotechnology is also facilitated by a similar system for storage and easy retrieval of genetic information, which can be stored in many formats. The genes can be decoded into DNA language or can be stored even in their physical form. >> Category: Biotech Research
  • The Role of DNA Recombinant Technology in Apple    By: Gayathri Raghavan

    Green Gene Technology (GGT), an integral part of modern biotechnology, has steadily progressed over the last decade. Countries such as India, United States, China, Canada, and Brazil have all turned towards GGT in recent times. Besides staple foods rice and wheat, fruits and vegetables were bred in order to generate quantitative and qualitative resistance traits. >> Category: Biotech Research
  • In-vitro Designing of SiRNA    By: Geetanjali Murari

    The in-silico designing of drug has brought a massive revolution the in the field of genetics and molecular biology. This article is based on the designing of small interfering RNA, its merits, work flow and applications. the ethical issue related to this discovery has also been mentioned. >> Category: Biotech Research
  • Benefits of the Human Genome Project    By: Geetanjali Murari

    This article depicts the utilities of complete sequencing of 3 billion DNA base pairs. The ethical, social and legal issues related to this project. The future challenges associated with the project and what are the researchers thinking beyond HGP (Human Genome Project). >> Category: Biotech Research


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