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  • Drug-Eluting Stents and Coronary Angioplasty    By: Meenu Kumar

    Percutaneous Transluminal Coronary Angioplasty (PTCA) is the procedure used to widen the coronary stenosis without the need for an open-surgical procedure. PTCA is also applied for treating stenosis of carotid arteries, which supply blood to the brain. >> Category: Biotech Research
  • The Role of Lactic Acid Bacteria in Preventing Respiratory Infections    By: Meenu Kumar

    The respiratory tract serves as the main pathway for pathogenic microorganisms to enter. Microorganisms replicate in the respiratory tract before spreading throughout the body. Acute lower respiratory tract infection (RTI) constitutes a pervasive and persistent health problem. >> Category: Biotech Research
  • Nanobiotechnology in Cardiovascular Disorders    By: Meenu Kumar

    Several nanosystems and nanodevices are available today for the sequencing of single DNA molecules. In the future, it is quite likely that numerous applications based on inorganic nanostructures will become available in medicine and biology as markers. >> Category: Biotech Research
  • Ethanologenic Bacteria and its Development    By: Meenu Kumar

    The rising cost of petroleum along with human dependency on crude-oil imports has opened up an opportunity for chemicals and bio-based fuels to become economically competitive. With new technologies developing on one side, petrochemicals and petroleum-based automotive fuels are effectively replaced with plant and plant-derived materials. >> Category: Biotech Research
  • Therapeutic Proteins and their Immunogenecity    By: Meenu Kumar

    In 1982, the first recombinant protein derived from DNA, for human use, was marketed as the human insulin. Since then, many recombinant proteins were introduced among which epoetins and interferons are some of the widely used drug products in the world today. >> Category: Biotech Research
  • DNA Microarrays and Design Formats    By: Meenu Kumar

    When physiological changes occur, some genes tend to become more active while other genes become inactive. In most biological processes, more than one gene is involved. In order to understand the functioning of an organism, scientists have examined many of an organism's life process simultaneously to understand how they respond to various changes over time. >> Category: Biotech Research
  • The Role of Monoclonal Antibody in Organ Transplant    By: Meenu Kumar

    Monoclonal antibodies are used in transplantation in order to prevent the host immune recognition of the donor tissue. Allograft tissue is impaired to the host immune response by two ways namely: antibody-mediated rejection and cellular-mediated rejection >> Category: Biotech Research
  • PET Scan in Stem Cell Therapy    By: Meenu Kumar

    Chronic heart failure is the major contributor to today's mortality and morbidity. It forms the final pathway for most heart disease forms among which coronary heart disease is the common contributor. >> Category: Biotech Research
  • The Role of Endometrial Cells in Treating Cardiac Failure    By: Meenu Kumar

    Heart failure, as we all know, is one of the major reasons of mortality and morbidity world-wide. Recent findings have stated that heart valve can undergo regeneration, which ideally can eliminate the usage of bovine and porcine valve replacements. This involves the usage of an effective allogeneic product, in conjunction with an effective delivery system. >> Category: Biotech Research
  • Industrial Biotechnology Evolution and Recent Developments    By: Gayathri Raghavan

    An Introduction to Industrial Biotechnology and its history. Industrial Biotechnology provides a wide range of new approaches to resource management, cost reduction in production, and tends to cater the higher requirements in Biotechnology, by targeting off-shoots at grass root level. Examples describing this third-wave biotechnology are the laboratory synthesis of Interleukins, monoclonal antibodies, Insulin. >> Category: Biotech Research
  • Biomarkers For Alzheimer's Disease    By: Geetanjali Murari

    This article deals with the treatment and diagnosis of the most common neurodegenerative disorder affecting many people worldwide. The early diagnosis of Alzheimer's would help the patients to cope up with the disease. >> Category: Biotech Research
  • Genomics Tools For Microbial Ecology: New Directions    By: Dr. Suresh Kaushik

    Microorganisms have been integral to the history and function of life on Earth. They have played important roles in Earth's climate, geological, geochemical and biological evolution. Microbial ecology examines the diversity and activity of microorganism in Earth's biosphere. The applications of genomics tools such as DNA cloning, DNA sequencing, polymerase chain reaction, DNA re-association kinetics analysis, fluorescent in situ hybridization (FISH), microarray technology, representational difference analysis, 2-D gel electrophoresis, mass spectrometry and gas chromatography have revolutionized microbial ecological studies. >> Category: Biotech Research
  • VRC01- New Vaccine to Target HIV    By: Geetanjali Murari

    Finding a cure for HIV/AIDS has always been a hot topic of research among the researchers and scientists. This article deals with the new vaccine designed to target the epidemic causing virus. >> Category: Biotech Research
  • Superhumans- Genetically Modified Humans    By: Geetanjali Murari

    We have seen many supernatural movies and read numerous novels related to superman. This fictitious character can do anything, make any impossible thing possible. But now this concept is no more imaginary. After producing genetically modified crops, vegetables, fruits, animals, now scientists are researching on genetically modified humans. Lets have a look at its consequences... >> Category: Biotech Research
  • ELQ-300 : The Invention of a New Anti-malarial Drug    By: Geetanjali Murari

    This article depicts the discovery of new drug which can combat the malarial parasite. The recent discovery was done under the Medicines for Malaria Venture (MMV) project which include Oregon Health & Science University in Portland, Drexel University in Philadelphia, and Monash University in Australia and University of South Florida. >> Category: Biotech Research
  • Assisted Reproduction- ICSI (Intra Cytoplasmic Sperm Injection)    By: Geetanjali Murari

    The innovative research in biotechnology has made every impossible work possible. The discovery of ICSI, an assisted reproduction can aid in the male infertility. Now, even the infertile men can have their own children. This article depicts the method, merits and risks associated with this technology. >> Category: Biotech Research
  • Genetic Information- Storage and Retrieval    By: Gayathri Raghavan

    In conventional sense, a library is an information repository that is catalogued for easy information retrieval and use. Biotechnology is also facilitated by a similar system for storage and easy retrieval of genetic information, which can be stored in many formats. The genes can be decoded into DNA language or can be stored even in their physical form. >> Category: Biotech Research
  • The Role of DNA Recombinant Technology in Apple    By: Gayathri Raghavan

    Green Gene Technology (GGT), an integral part of modern biotechnology, has steadily progressed over the last decade. Countries such as India, United States, China, Canada, and Brazil have all turned towards GGT in recent times. Besides staple foods rice and wheat, fruits and vegetables were bred in order to generate quantitative and qualitative resistance traits. >> Category: Biotech Research
  • In-vitro Designing of SiRNA    By: Geetanjali Murari

    The in-silico designing of drug has brought a massive revolution the in the field of genetics and molecular biology. This article is based on the designing of small interfering RNA, its merits, work flow and applications. the ethical issue related to this discovery has also been mentioned. >> Category: Biotech Research
  • Benefits of the Human Genome Project    By: Geetanjali Murari

    This article depicts the utilities of complete sequencing of 3 billion DNA base pairs. The ethical, social and legal issues related to this project. The future challenges associated with the project and what are the researchers thinking beyond HGP (Human Genome Project). >> Category: Biotech Research
  • Protein Purification Process: The Various Techniques Involved    By: Gayathri Raghavan

    Tremendous success in the fields of genetic engineering and molecular biology has enabled scientists to express any amino acid sequence and practically synthesize any protein. But, this success depends on one key factor; in order for the expressed proteins to be used commercially, it should be purified to a certain degree. >> Category: Biotech Research
  • Red and Green Biotechnology    By: Gayathri Raghavan

    Biotechnology is huge; its exact boundaries cannot be defined. European scientists have divided biotechnology into two categories: red biotechnology and green biotechnology. Red biotechnology deals with medicine while green biotechnology deals with food. Some scientists have further divided biotechnology into blue and white biotechnology. >> Category: Biotech Research
  • The Process of Mammalian Cell Culturing    By: Gayathri Raghavan

    In order to improve the performance of immobilized- cell cultures, modern-day scientists primarily focused on two objectives: (1) provide cells with optimum- growth conditions; (2) obtain large quantities of products of high concentration at low cost. In majority of the cases, optimal conditions for product formation and cell growth differ from each other. >> Category: Biotech Research
  • Role of Hollow-Fiber Process    By: Gayathri Raghavan

    Biotechnology began with recombinant DNA technology, cell fusion techniques, and protein production techniques. With advances in genomics, numerous biological targets are likely to be identified, paving way for generating a wider array of products. >> Category: Biotech Research
  • Importance of Genomics    By: Gayathri Raghavan

    The scientific discipline involving mapping, analyzing, and sequencing genomes is known as genomics. In drug development, functional genomics combines with methodologies such as bioinformatics, animal model, and DNA chip technology in order to identify and characterize the genes that are responsible for human diseases. >> Category: Biotech Research
  • Metabolic Pathways in Molecular Genetics    By: Gayathri Raghavan

    Cells derive energy from nutrients to synthesize compounds required for life reproduction and functions. This energy is provided by biochemical reactions that form a biochemical network systems called as metabolic pathways. Molecules that flow through the metabolic pathways are due to the response of environmental stress. >> Category: Biotech Research
  • Recombinant Proteins Produced in Genetically Engineered Crops    By: Dr. Suresh Kaushik

    Production of recombinant proteins in seed for genetically enhanced plants will revolutionize the industry with biotech products that are easier to produce, safer and cost less to produce. Use of plants as a recombinant protein expression system will hold great promise for the future. >> Category: Biotech Research
  • Stem Cells Types and Therapeutics    By: Gayathri Raghavan

    Even before tissue engineering and regenerative medicine took shape, scientists have known about the fact that animals like the star fish were capable of regenerating missing body parts. Although, humans share this ability, humans cannot regenerate a missing finger or toe. Instead, the human body constantly regenerates skin cells, blood cells, and tissues. >> Category: Biotech Research
  • Understanding Genetic Disorders in Human Genetics    By: Gayathri Raghavan

    The concept of genetic disorder was relatively unknown before the 1900s. But, after William Bateson suggested the term 'genetics' in 1906, scientists began learning and understanding more about genetics and heredity. Any abnormality in the DNA of an individual's gene is called genetic disorder. >> Category: Biotech Research
  • Applications and Advantages of Molecular Markers in Plants    By: sippy ISSAC

    Genetic improvement of crop plant through conventional plant breeding has made tremendous contribution to the breakthrough in the global agricultural production. Recently, arrays of tools and techniques in the field of molecular biology have become available for supplementing the conventional genetic approaches. >> Category: Biotech Research
  • Medicinal Uses of Cassia Auriculata    By: Narmadha D

    The phytochemical variation and antimicrobial activity has been assessed among the Cassia auriculata leaves, flowers, and seeds. Hence it can be known that Cassia auriculata as 'Avaram' for its potential diabetic value. Besides this has high protein and tannin content which adds to the quality of the antimicrobial activity and essential yellow dye extraction. >> Category: Biotech Research
  • Silver Staining- Developing Photogenic Gels!!    By: kashika arora

    Among different methods for staining gels, silver staining has come up with many advantages as great sensitivity and ease in further analysis by MALDI - MS. It is important to know how it works to develop beautiful gels. >> Category: Biotech Research
  • Genomics and Its Applications in Agriculture    By: Medha Hegde

    Agricultural genomics is concerned with the research and development activities in agriculture that have obvious potential to translate genomic technology in agronomic advancement. >> Category: Biotech Research
  • Yeast Artifical Chromosomes (YACs) and their Applications    By: Medha Hegde

    YAC is an artificially built chromosome and includes the centromere, telomere and autonomously replicating sequences essential for replication and conservation in yeast cells. >> Category: Biotech Research
  • Effect of Microgravity on Immune Cell Signal Transduction Pathways    By: Shivani Sharma

    NASA has been organizing various space missions ever since the early 90s. Astronauts generally experience a non-gravity field during space flights. This condition is generally denoted as a zero gravity or more commonly, microgravity. Microgravity has been found out effect the basic signal transduction pathways of immune cells in human body. Though the exact mechanisms are still not known, there ha >> Category: Biotech Research
  • Artificial Blood - An Application of Recombinant DNA Technology    By: Shivani Sharma

    Blood, not only provides life, but is the key source of oxygen delivery to the tissues and organs within the body. Successful blood transfusions have saved many lives during conditions where most or whole blood of an organism has been wasted away due to some accident or other mishap. Transfusion of small amounts of blood is very usual and doesn't experience any problems while large amount of blood >> Category: Biotech Research
  • DNA Computing- Using DNA as a Computational Device.    By: Shivani Sharma

    DNA or Molecular computing basically suggests the use of DNA and biological components for computational purposes. It has been a long seen dream of bio-nanotechnologist to achieve the ultimate goal of computing utilizing DNA. In DNA computing, instead of creation of millions of proteins that bind along the DNA sequence in order to express a gene, researchers have thought of a new approach. >> Category: Biotech Research
  • Genetic Abnormalties in Cytoskeleton in Microgravity    By: Shivani Sharma

    Based on the published study, Effect of microgravity on cell cytoskeleton and embryogenesis by Susan J crowford-Young, it can be said that quite a good amount of work has been done on the influence of microgravity on microtubules and there were quite noticeable differences that were observed in the organization of patterns in 1G earth gravity and then in microgravity. >> Category: Biotech Research
  • Artificial Life: Creating Organisms From Genetic Blueprint | Poliovirus    By: Shivani Sharma

    The first step has been taken by three researchers named Jeronimo Cello, Aniko Paul and Eckard Wimmer. They used all the genomic data available for a virus and then they build a fully functional virus from the scratch. They have successfully created a polio virus which appears entirely normal and have its usual functional characteristics. Their discovery has made an ever remarkable note in the boo >> Category: Biotech Research
  • Chimeras: Part Human Animals    By: Shivani Sharma

    Fred Gage, a biologist at the Salk Institute created some part-human animals to understand the basic mechanisms underlying the question how human neurons degrade in people suffering from neurodegenerative diseases for instance, Parkinson's and Alzheimer's. Studying and perturbing brain cells in their natural environment that is inside a functioning brain do provide the best hope and methods for de >> Category: Biotech Research
  • Dark Side of Respiratory Chain: Superoxide Formation | Aging & Cell Death    By: Shivani Sharma

    While on one hand the ETC contribute to cell-growth and cell survival by producing chemical energy in the form of ATP derived from the electrochemical gradient across the inner mitochondrial membrane, the premature leakage of oxygen at the major two sites viz. complex I and II leading to formation of harmful superoxide could be fatal and contributes to many pathological factors including agi >> Category: Biotech Research
  • Alterations in Signal Transduction Due to Microgravity    By: Shivani Sharma

    Astronauts sent into space by NASA and other space programmes constantly deal with several factors in order to survive in a zero-gravity field. Obviously in a non-gravity field like space with extremely alien conditions, it does get difficult to adapt and continue the basic necessary metabolic processes. Although not as fatal as to cause death or the severe harmful effects on human body, the absen >> Category: Biotech Research
  • Mutants on the Face of Earth: The Evidence That Humans Are Still Evolving.    By: Shivani Sharma

    Mutants do exist although not as depicted in exaggerated sci-fi shows. From a small to a large mutation, various examples lie widespread on the face of earth pointing out the presence of humans with extra-ordinary capabilities possibly caused due to sudden changes in their DNA sequences, gene pattern or motifs leading to a change in the normal gene expression ultimately causing an alteration in ... >> Category: Biotech Research
  • Boule Gene is Responsible for Sperm Production - The Universal Sexy Gene    By: Shivani Sharma

    The birth of an organism usually takes an egg and a sperm; the sperm needs to be fused with the egg in order to help develop it into a zygote for the formation of an offspring and then the birth of a child leads thereafter. These two factors are essential for life and for the recent decades their origin esp. of the sperm has been an interesting question which has led many studies on the origin and >> Category: Biotech Research
  • Canadians Weigh Less Than Their American: Low-Gravity Regions on Earth    By: Shivani Sharma

    Over the past few decades, significant research work have revealed that there are certain low gravity regions on Earth. As we know the g-value on earth is 9.8 m/s or 1 approximately. But in these regions, the level of gravity is lower than the normal g-value causing major impact on the thriving environment and the surroundings. It can be quite surprising to know that the Canadians weigh less than >> Category: Biotech Research
  • Microbes Fly to the Space: Enhanced Virulence Factor    By: Shivani Sharma

    Microbes or pathogens to be specific, are known to experience some unique low fluid shear forces in space that are quite similar in nature to those experienced within a live organism's body on earth. Research work funded by NASA has clearly revealed that the microbial virulence is enhanced when the bacterial cultures are provided an environment of microgravity. It is well known that the ability o >> Category: Biotech Research
  • Bioluminiscence - Emission of Light From Living Organisms    By: Medha Hegde

    Bioluminiscence is a type of chemiluminiscence where light generating chemical reaction occurs inside an organism (like insects). A wide range of organisms are gifted with the ability to produce light and to exhibit and manage it in a variety of ways >> Category: Biotech Research
  • Ribozymes - the Catalytic RNA's    By: Medha Hegde

    RNA molecule that function as enzymes, regularly found to catalyse the cleavage of its own or other RNA's .That is RNA's that act as enzymes are known as Ribozymes >> Category: Biotech Research
  • Lignocellulosic Biodegradation of Coir Fibre by Microorganisms    By: soumya T.V

    Lignin is the most abundant renewable aromatic material on earth.The aromatic polymer is well-known for resistance to microbial degradation because of its high molecular weight and presence of various biologically stable carbon-to-carbon and ether linkages.Lignin degradation by the white rot fungi is a complex secondary metabolic process mediated by the action of several extra cellular enzymes. >> Category: Biotech Research
  • Next Generation Sequencing (NGS): The Next Step in Personalized Medicine    By: Chandra Kala

    NGS technique is a kind of high throughput data DNA sequencing and integrates various strategies of sequencing, genome assembly and alignment to fasten the sequencing procedure and to reduce the error in sequencing. The development of NGS made many previously utilized techniques obsolete. NGS has high demand in the human health industry focusing on personalized medicine. >> Category: Biotech Research

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