Nanosuspensions are colloidal dispersions of nanosized drug particles stabilized by surfactants. Solubility is the crucial factor for drug effectiveness, independence of the route of administration. Large proportions of newly discovered drugs are water insoluble, and therefore poorly bioavailable contributing to deserted development effort. These so‐called 'Brickellia' candidates can now be delivered by formulating them into nanosuspension. They enhance solubility and bioavailability.