Author: Priyanka Chaudhary
Total Articles: 3 |
Total Views: 14983
| Points Scored: 16,483
City: Ghaziabad |
State: Uttar Pradesh
About Me: Pursuing M. Phil.
Articles by Priyanka Chaudhary:
Zinc Finger Nuclease (ZFN) - Modify human genome precisely and efficiently
( 8316 reads)
It is possible to target the DNA sequences probing gene function. Designer zinc finger proteins (ZFPs) are the sequence specific tools which are used to manipulate a gene of interest at genomic level. Several methods are being used to modify the human genome precisely and efficiently. These methods hold great promise to revolutionize the gene therapy arena. One of these promising technologies ZFN.
DNAzymes: Introduction and DNAzymes in Cancer Treatment
( 2994 reads)
DNAzymes are the highly useful tools in molecular biology and now-a-days they are being used in clinical research. DNAzymes are the potent analytic tool available to molecular biologists. There are several techniques which are used for gene silencing which include DNAzymes, short interfering RNAs (siRNAs), antisense oligonucleotides and the ribozymes mainly.
RNA-Interference (RNAi) : History, Mechanism and Applications
( 3673 reads)
The term transcriptional gene silencing (TGS) and post transcriptional gene silencing (PTGS) are highly effective methods in gene silencing. Post transcriptional gene silencing results from sequence specific mRNA degradation in the cytoplasm without any specific changes in transcription of the respective gene in nucleus. Transcriptional gene silencing (TGS) and post transcriptional gene